The Mitostream® Technology
The Mitostream® technology is a cellular dynamical system approach using the intracellular self-organizing dynamic organelle, the mitochondria as a readout.
| WHAT IT IS | WHAT IT’S NOT (ie. Mitosafe®) |
|
|
Mitostream® = In cell insight
Mitostream® is a patented cellular dynamical system technology that encompasses the whole complexity of the mitochondrial interactions within its cellular environment, measuring its resultant: The mitochondrial behavior.
It represents the simultaneous measure of HCA variables contained within four dimensions defining the mitochondrial behavior:
- The mitochondrial motility,
- The mitochondrial morphology,
- The mitochondrial reticular network organization and
- The mitochondrial permeability.
We analyze dynamic and static images of mitochondria in live cells allowing for the characterization of disease state or of dose-response to a tested drug, either a chemical or a biological.
Validating drugs targeting multiple neurodegenerative disease etiology
Our scientists have characterized specific mitochondrial behavior patterns in normal and disease states (patents pending) and propose the qualification of disease-modifying properties of your compounds in vitro in a HCA format.
We have validated a Huntington’s disease model and are looking for partnerships in the validation of an Alzheimer’s disease model and of a muscular dystrophy model using human primary tissue.


